Carcinogenesis Studies with Benzoyl Peroxide (Panoxyl Gel 5%)
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چکیده
منابع مشابه
Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne.
Acne is the most common skin disease, with a relative prevalence of 85%-100% among young individuals. It affects the cosmetic appearance of the patients provoking severe distress. A number of different topical treatments have been used for the treatment of acne. In this study, we investigated the efficacy and safety of the topical treatment with 5% benzoyl peroxide and 3% erythromycin gel in pa...
متن کاملComparing a novel solubilized benzoyl peroxide gel with benzoyl peroxide/clindamycin: final data from a multicenter, investigator-blind, randomized study.
INTRODUCTION A solubilized 5% BPO gel has been developed to enhance the bioavailability, follicular penetration, and efficacy of BPO. METHODS Sixty-five patients with moderate facial acne vulgaris were randomly assigned to apply solubilized 5% BPO gel to one facial side and 5% BPO/1% clindamycin to the contralateral side, twice daily for four or 12 weeks. RESULTS The solubilized BPO gel res...
متن کاملTretinoin and Benzoyl Peroxide
A simple, sensitive, spectrophotometric method in UV region has been developed for the simultaneous estimation of benzoyl peroxide and tretinoin in bulk and semi solid dosage form (cream). Standard solution of benzoyl peroxide shows maximum absorbance at 234.8 nm and tretinoin shows maximum absorbance at 348.6 nm. Beer’s Lamberts law is obeyed in concentration range 1-9 μg/ml for tretinoin with...
متن کاملProfile of clindamycin phosphate 1.2%/benzoyl peroxide 3.75% aqueous gel for the treatment of acne vulgaris
Acne vulgaris is a common and chronic skin disease, and is a frequent source of morbidity for affected patients. Treatment of acne vulgaris is often difficult due to the multifactorial nature of this disease. Combination therapy, such as that containing clindamycin and benzoyl peroxide, has become the standard of care. Several fixed formulations of clindamycin 1% and benzoyl peroxide of varying...
متن کامل3-Benzoyl-5-chlorouracil
THE DIHEDRAL ANGLE BETWEEN THE PLANES OF TWO AROMATIC RINGS IN THE TITLE COMPOUND [SYSTEMATIC NAME: 3-benzoyl-5-chloro-pyrimidine-2,4(1H,3H)-dione], C(11)H(7)ClN(2)O(3), is 86.79 (6)°. Centrosymmetric dimers formed by N-H⋯O hydrogen bonds are linked through C-H⋯O inter-actions, forming a two-dimensional network parallel to (10).
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1986
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12285787